Core facility

Equipment

AVS-1.1 automated voltammetry system (2006)
The system is made up of an AVS-1.1 analyzer and a computer (PC). The instrument is controlled and the measurements are processed by means of a PC program supplied along with the device. All information coming from the instrument appears on PC display. Voltammetric analyzer AVS-1.1 facilitates all types of voltammetry on solid electrodes for analyzing heavy metal content in drinking, natural, and waste water, in food products, in biological and other materials. The device can operate with a 3-electrode electrochemical cell. The main operating mode for the heavy metal analyzer is square-wave AC stripping voltammetry. The measurement range of the mass fraction of metals in sample is 0.001-250 mg/kg depending on the metal. Permissible standard deviation for the random error component is ±20 % in the 1 to 10 µg/dm3 range and ±15% in the >10 to 100 µg/dm3 range; for the systematic error: ±20 % in the 1 to 10 µg/dm3 range and ±15% in the >10 to 100 µg/dm3 range.
Operating cost price per hour starts at RUR 300.

MaxyGene II Therm-1000 amplifier (thermal cycler) (2013)
Intended for nucleic acid amplification by polymerase chain reaction. Performs a pre-set number of thermal cycles (alternating heating and cooling steps). Can be used to run any cyclic thermal reaction.
Operating cost price per hour starts at RUR 200.

T100 amplifier (thermal cycler) (2019)
Intended for nucleic acid amplification by polymerase chain reaction. The temperature gradient function helps determine optimal reaction parameters; large touch screen facilitates quick and easy control. The thermal cycler is supplied with a countdown timer with large, high-contrast symbols visible from afar, showing time until reaction completion. Heated lid permits PCR to be run without mineral oil. Amplifier Ò100 is registered in Russia and included in the State Register of Medical Devices.
Operating cost price per hour starts at RUR 200.

C1000 amplifier with CFX96 optical reaction module (2015)
For PCR analysis permitting detection of reaction products in real time. Capabilities: •Real-time PCR (up to 5 targets per well); • Endpoint PCR; • PCR without endpoint determination; • Determination of optimal temperature for PCR.
Operating cost price per hour starts at RUR 200.

Malvern particle and molecular size analyzer with Zetasizer Nano ZS (2010)
A high performance two angle particle and molecular size analyzer for the enhanced detection of aggregates and measurement of small or dilute samples, and samples at very high concentration using dynamic light scattering with ‘NIBS’ optics. The ZSP also incorporates a zeta potential analyzer that uses electrophoretic light scattering for particles, molecules and surfaces, and a molecular weight analyzer using static light scattering.
Operating cost price per hour starts at RUR 400.

MINI-PAM (655 nm) photosynthesis yield analyzer (2004)
Determination of effective quantum yield photochemical energy conversion in photosystem II. Max light emission - 650 nm, PAR intensity - 0.15 µmol m-2s-1, modulation frequency 20 kHz.
Operating cost price per hour starts at RUR 400.

NOV400 atomic absorption spectrometer (2004)
Compact spectrometer, single- and double-beam, with flame and transverse heated graphite atomizer, with 6-lamp turret. For single-element sequential atomic absorption analysis with flame, electrothermal atomization and deuterium background correction.
Operating cost price per hour starts at RUR 300.

ÀÀ 6200 atomic absorption spectrophotometer with flame atomizer (2006)
Single-element sequential atomic absorption analysis with flame atomization and deuterium background correction. Spectral range is 190-900 nm. Relative standard deviation of the output signal in the flame atomization mode is 5.0%.
Operating cost price per hour starts at RUR 500.

ÀÀ-6800 atomic absorption spectrophotometer (2002)
Designed for quantitative elemental analysis of the content of elements (chiefly metals) based on atomic absorption spectra obtained by flame (ppm) and electrothermal (ppb) atomization in plant, animal, water, and soil samples.
Operating cost price per hour starts at RUR 500.

ÀÀ 6800 atomic absorption spectrophotometer with flame and electrothermal atomizer (2003)
Single-element sequential atomic absorption analysis with flame and electrothermal atomization and two background correction systems: by deuterium lamp (D2) and based on line self-reversal (SR). Spectrometer with 8-lamp turret. Spectral range is 190-900 nm. Relative standard deviation of the output signal in the flame atomization mode is 2.0%; in the electrothermal atomization mode – 7.0%.
Operating cost price per hour starts at RUR 500.

ÀÀ-7000F atomic absorption spectrophotometer (2012)
Designed for quantitative elemental analysis of the content of elements (chiefly metals) based on atomic absorption spectra obtained by flame (ppm) and electrothermal (ppb) atomization in plant, animal, water, and soil samples.
Operating cost price per hour starts at RUR 500.

ARL ADVANT"X wavelength X-ray fluorescence spectrometer (2010)
Quantitative analysis of the following elements is done using melted samples: Al2O3, Fe2O3îáù., Na2O, CaO, K2O, MgO, MnO, TiO2, P2O5. Qualitative analysis (from Na to Am).
Operating cost price per hour starts at RUR 700.

T-BLADE computing cluster (2008)
The computing cluster is designed for doing high-throughput computing for data modeling and processing.

ChemiDoc gel documentation system (2016)
Analysis of agarose gels, colorimetric analysis of polyacrylamide gels, detection of 2D phoresis results, multiplex fluorescence, chemiluminescence.
Operating cost price per hour starts at RUR 200.

MICROM histology system (2009)
The system includes carousel tissue processor STP 120, paraffin embedding center ÅÑ 350, sliding microtome ÍÌ 450. Intended for histological analysis of organ tissues for the study of their structure, morphology, chemical composition and functions of certain structures in tissues.
Operating cost price per hour starts at RUR 200.

Hei-VAP rotary evaporator (2019)
Laboratory rotary evaporator Hei-VAP is suitable for most of standard evaporation tasks.
Operating cost price per hour starts at RUR 100.

Trans-Blot® SD Semi-Dry Transfer Cell (2010)
The trans-blot cell is used in biochemical research to transfer complex protein mixtures from polyacrylamide gel to nitrocellulose membrane for subsequent identification of protein fractions by means of their detection in the antibody-bound form (immunoblotting, or Western blot analysis), which is a necessary step in isolation and purification protocols.
Operating cost price per hour starts at RUR 200.

ECD01E climate chamber (2013)
Intended for staging experiments in the study of the parameters of physiological and biochemical processes in plants.
Operating cost price per hour starts at RUR 200.

VB 1014 climate chamber (2011)
Intended for staging experiments in the study of the parameters of physiological and biochemical processes in plants.
Operating cost price per hour starts at RUR 200.

System for preparing samples for FC 500 cytometer, made up of COULTER PrepPlus 2 sample preparation workstation and TQ-Prep automatic lysing system (2009)
Designed for automated preparation of samples for the analysis of living cell properties by flow cytometry. By connecting PrepPlus laboratory workstation to TQ-Prep station, an integrated laboratory system is created that enables full automation of the sample preparation process. PrepPlus workstation provides precision pipetting of reagents, clinical samples, controls and calibrators into daughter tubes. PrepPlus workstation is operated using TQ-Prep touchscreen. Furthermore, cell lysis by TQ-Prep is automatic, requiring very little human operator involvement in the sample preparation process.
Operating cost price per hour starts at RUR 400.

LI-8100 A laboratory installation for measuring and logging carbon and water exchange parameters (2011)
Intended for determination of a number of carbon and water exchange parameters in plant objects.
Operating cost price per hour starts at RUR 300.

LS-13320 laser particle size analyzer (2009)
Particle size analyzer LS 13 320 manufactured by ÂÅÑÊÌÀN COULTER is intended for determining the grain size composition of ground samples. Covers the size range of 0.04 to 2000 µm, in conformance with ISO 13320-1.
Operating cost price per hour starts at RUR 500.

FreeZone 6L freeze dryer (to -50°Ñ) (2011)
Designed for dewatering biological objects in low-temperature and vacuum settings: tissues, proteins, nucleic acids, vaccines, etc. by lyophilizing (freeze drying organic samples in the vacuum) for long-term storage.
Operating cost price per hour starts at RUR 100.

Agilent 7500à inductively coupled plasma mass spectrometer (2009)
Quantitative elemental analysis of drinking-, natural-, wastewater, atmospheric fallouts, bottom sediments. Control of the state of the environment. Sensitivity (cps per 1 mg/dm3 of the element being detected): 8·106 (7Li), 20·106 (89Y), 12·106 (205Tl); Background for peaks at 5 amu: 5 cps; Relative oxide ion content (156ÑåÎ+/140Ñå+) within 1%; Relative double-charged ion content (70Ñå++/140Ñå+) within 3%; Relative standard deviation of the random error component of the analytical signal of mass peaks for Li (7), Y(89), Tl (205) over 20 minutes of operation within 3%. Data processing: ICP-MS ChemStation.
Operating cost price per hour starts at RUR 800.

X Series 2+UP-266 Macro inductively coupled plasma mass spectrometer with laser ablation system (2007).
Elemental analysis of rocks, soils, ceramics, water. Sensitivity (MP·ppm s) at least 6 (7Li), 15 (59Co), 40 (115In), 80 (238U) with a standard Xt interface; Background at 5, 110, and 220 amu below 0.5 cps; Signal-to-noise ratio at least 80×106 (115 In/220 amu); Oxide ion content (ÑåÎ/Ñå) within 2% (Peltier cooler); Double-charged ion content (Âà++/Âà+) within 3%; Short-term result stability – 2%, long-term stability – 3%; Dynamic range: over 9 orders of magnitude.
Operating cost price per hour starts at RUR 1100.

Speedwave SW 4 microwave digestion system (2012)
Autoclave digestion of samples at temperatures up to 230°Ñ in lengthy processes (up to 300°Ñ over short intervals) depending on the digester, at pressures up to 100 Bar (1450 psi). Microwave field output up to 1450 W at 2.45 GHz frequency. Controlled by a module with minicomputer power PC5200.
Operating cost price per hour starts at RUR 100.

Speedwave Four microwave digestion system with non-contact pressure and temperature control (2009)
Designed for sample digestion under the action of high temperature and pressure arising in microwave field for subsequent determination of elements contained in the samples.
Operating cost price per hour starts at RUR 100.

Microwave digester (ÌS-6) and photolytic chamber (FK-12M) system (2007)
The system is designed for digesting (ashing) biological samples of varying genesis for chemical composition analysis by different methods: voltammetry, atomic absorption spectroscopy, spectrophotometry, etc.
Operating cost price per hour starts at RUR 100.

Olympus ÑÕ41RF-5 microscope with integrated VIDI-CAM digital module (2010)
Designed for microscopic examination of samples, image capturing, preparation of databases with images, as well as for manual morphometric analysis of computer-generated images (estimation of dimensions and optical characteristics, number of objects, shape, area occupied).
Operating cost price per hour starts at RUR 100.

BiOptik BI-200 series inverted laboratory microscope (2016)
Applied in cell cultivation, experiments with labeled proteins and other research activities. Suitable for working with tissue cultures.
Operating cost price per hour starts at RUR 100.

Axioscope 40FL-1 optical microscope with digital video camera and VideoTest software (2001)
Designed for transmitted-light microscopic examination of samples, image capturing, preparation of databases with images, as well as for manual and automatic morphometric analysis of computer-generated images (estimation of dimensions and optical characteristics, number of objects, shape, area occupied). Objectives õ5-õ100 (with oil immersion), eyepieces õ10, video camera image capture speed – 100-500 ms, video recording.
Operating cost price per hour starts at RUR 100.

AxioScope À1 upright microscope with digital video camera and AxioVision À1 software (2010)
Designed for microscopic examination of samples, image capturing, preparation of databases with images, as well as for manual morphometric analysis of computer-generated images (estimation of dimensions and optical characteristics, number of objects, shape, area occupied). Objectives õ10-õ100 (with oil and water immersion), eyepieces õ10, video camera image capture speed 10-500 ms, video recording. Microscopy can be done in transmitted light, in dark field, with phase contrast and with fluorescence. Possibility of overlaying several channels.
Operating cost price per hour starts at RUR 100.

Olympus CX41 light microscope (2011) with ProgRes C10plus digital color image capture system, PC with monitor and VideoTest 5.0 software (2007)
Used in studying the structure of organ and tissue cells, for qualitative and quantitative analysis of the composition of lipids, proteins, enzymes and their localization in cells of different organs and tissues by means of histological and histochemical methods, for measuring cells and cellular structures, for obtaining and processing their images. Eyepiece õ10; objectives 10õ, 20õ, 40õ, 100õ. Smallest measurable size 1 µm. Designed for software rendering of morphological specimens, analysis and documentation of optical and morphological parameters.
Operating cost price per hour starts at RUR 100.

VK-9710 surface analysis module for laser scanning microscope (2011)
KEYENCE VK9700 applications include: - measuring the height, width, cross-section, angle or radius of any user-selected cross-sectional profile; - non-contact measurement in XYZ coordinates, 3D measurements, profilometry, measurement of line roughness, and high-precision measurement of the surface roughness of any specified area; - measurement of the volume, surface area and ratio of area to surface area of objects; automatic measurement of the height and width of structures; - comparative measurement of objects by image overlaying.
Operating cost price per hour starts at RUR 100.

Nano DSC nanocalorimetry unit (2010)
Designed for determining the thermal stability and heat capacity of proteins and other macromolecules in dilute solutions, permitting flexible and accurate screening of molecular stability, ligand binding, and pressure-initiated measurements.
Operating cost price per hour starts at RUR 400.

CLARIOstar monochromator plate reader with fluorimeter, luminometer, spectrophotometer (2015)
As opposed to readers with classical monochromators, CLARIOstar® multi-mode reader can vary entrance slit width from 8 to 100 nm, which enhances its sensitivity considerably. Improved ease of operation owing to the fluorophore library integrated in the software. The reader is equipped with a specialized LVF monochromator, highly sensitive filters, and ultra-fast spectrometer. Performs eight types of measurements: Fluorescence intensity (FI), Fluorescence resonance energy transfer (FRET), Fluorescence polarization (FP), AlphaScreen®/ AlphaLISA® (AS/AL), Luminescence (flash and glow) (LUM), Bioluminescence resonance energy transfer (BRET), Time-resolved fluorescence – including time-resolved fluorescence resonance energy transfer (TRF/TR-FRET), and UV/viz absorbance (ABS).
Operating cost price per hour starts at RUR 100.

LI-6400XTP portable photosynthesis system (2009)
Designed for determining a spectrum of photosynthesis parameters in plant objects.
Operating cost price per hour starts at RUR 400.

FC500 flow cytometer (2007)
A universal system designed for biomedical research based on the analysis of living cell properties. Delivers high precision information on cell morphology, surface antigens, activity of intracellular enzymes and cytokines, permits measuring physiological parameters of the cell.
Operating cost price per hour starts at RUR 400.

ÅÌÕ-6/1 electron paramagnetic resonance spectroradiometer with ER4131VT temperature control system (2002)
Records the spectra of electron paramagnetic resonance of paramagnetic centers in substance. Controls the thermal regime of measurements in EPR spectroscopy.
Operating cost price per hour starts at RUR 400.

Nicolet Almega XR dispersive Raman spectrometer (2011)
Nicolet Almega XR is designed for determining the content of various organic and inorganic substances in solid, liquid and gaseous samples, food products, soils, etc. using Raman spectra. Excitation laser wavelength, nm - 785, 532; Spectral range, cm - 100...4000; Spectral resolution, cm, within 2.0; Absolute error allowance for wave-number scale, cm -1.0. The spectrometer is an automated benchtop instrument made of a monochromator, laser and detector, optical sample illumination system, and electronics.
Operating cost price per hour starts at RUR 200.

ARL X'TRA X-ray diffractometer (2009)
Determination of sample phase composition. Crystallography.
Operating cost price per hour starts at RUR 500.

CHNS/O elemental analyzer 2400 Series II (2002)
Designed for determining the per cent content of C, H, N, S, and O in various organic samples through combustion in an oxygen environment. Combustion products are separated by displacement chromatography and detection is performed by a highly stable thermal conductivity detector.
Operating cost price per hour starts at RUR 700.

BioSan S-Bt Smart Biotherm CO2 incubator (2017)
Used to create reproducible optimal settings for cell culture growth.
Operating cost price per hour starts at RUR 100.

Areol and CytoVision Areol SL-50 system (2010)
The system analyzes samples in white light and using fluorescence methods. Quickly scanning the sample, the instrument quantifies biomarkers in immunohistochemical, immunofluorescent assays, in fluorescence in situ hybridization (FISH) reaction. CytoVision permits to quickly scan the sample, detect cells in metaphase, perform karyotyping, analyze the results of fluorescence in situ hybridization (FISH), multicolor fluorescence in situ hybridization (M-FISH), multiple chromosome banding (RxFISH).
Operating cost price per hour starts at RUR 400.

CEQ 8000 genetic analysis system (2008)
The genetic analysis system performs reliable automatic DNA sequencing, analysis of enzymes, estimation of genetic diversity, identifies differences in the sequence at up to one nucleotide precision, helps identify the coding region, detect point (gene) mutations associated with metabolic and immunodeficiency disorders in animals and humans, pigment mutations in plants, identify alleles.
Operating cost price per hour starts at RUR 400.

ÍÑÌ-1000 photosynthesis measurement system (2004)
Used for measuring the rates of photosynthesis, respiration and transpiration based on changes in carbon dioxide and water vapor levels. Measurement range from -50 to +50 ððì ÑÎ2 and from 0 to 5000 ððì Í2Î. Flux – 600-1000 ml/min.
Operating cost price per hour starts at RUR 400.

Oxygraph Plus photosynthesis and respiration measurement system (2014)
Oxygraph Plus system is a high-performance instrument for measuring the oxygen signal from Clark-type polarographic electrode (type S1). The electrode guarantees quick calibration and easy configuring of the system. The system features an integral magnetic stirrer. The DW1/AD electrode chamber is gas-tight, with construction providing excellent sample visibility and uniform illumination by natural light. Functions include DW1/AD chamber thermal regulation, measurement calibration, recording, storage and analysis of measured data using Windows® software. The measuring range with liquid- and gas-phase oxygen is 0-100%. Sampling rate – 1 reading/s, maximum continuous measurement duration – 14 hours. Possibility of additional measurements (auxiliary port, pH electrodes, ion-selective electrodes) at 16 bit resolution.
Operating cost price per hour starts at RUR 400.

Simplisity water purification system (2014)
Compact system for obtaining ultrapure water (grade 1 according to GOST R 52501-2005 standard) from water pretreated by reverse osmosis, distillation or deionization. Water of this purity grade is required for instrumental analysis methods: atomic absorption and atomic emission spectroscopy, HPLC, LC, mass spectrometric analysis techniques (GC-MS and ICP-MS); for capillary electrophoresis, etc.; in molecular biology; for two-dimensional electrophoresis; for toxicological studies.
Operating cost price per hour starts at RUR 100.

IQ iCycler real-time PCR system, RNA analysis system (2006)
Automatic detection of PCR product concentrations in the process of amplification.
This automated protein and RNA analysis system is designed for separation of plant and animal proteins, enzymes and RNA and is supplied with a computer and software for automatic identification.
Operating cost price per hour starts at RUR 200.

Vega INCA Energy-350 scanning microscope with energy dispersive analyzer (2006)
Scanning electron microscope Tescan VEGA II LSH is designed for imaging and examining the surface morphology of solid samples at high spatial resolutions and for qualitative and quantitative elemental EDX analysis capable of detecting elements following beryllium.
Specifications: Resolution: 3.0 nm at 30 kV. Magnification: 4× to 1 000 000×. Accelerating voltage: 200 V to 30 kV. Probe current: 1 pA to 2 µA. Electron gun: tungsten cathode with thermionic emission. Scanning rate: 200 ns to 10 ms per point. Detectors: ET-type secondary electron (SE) detector; highly sensitive backscattered electron (BSE) detector; INCA Energy 350 energy dispersive detector, chamberscope.
Operating cost price per hour starts at RUR 600.

STA 499 F1 simultaneous thermal analyzer (2011)
STA 449 F1 Jupiter® measures the calorimetric effects (of phase transition temperature and enthalpy) and mass change with high resolution and precision. Furthermore, the device combines high-precision technical characteristics of DSC heat flow and a world’s pioneering thermonanobalance system, which has augmented the resolution and reduced noise and drift. Â STA 449 F1 Jupiter® features a high resolution of TG signal (0.025 µg or 25 ng) with a wide measurement range of up to 5 g (in a widest possible temperature range (20°C to 2000°)).
Operating cost price per hour starts at RUR 200.

SF-2000 spectrophotometer (2009)
Designed for measuring spectral coefficients of regular transmittance for liquid samples. Spectral range: 200 to 1100 nm, error allowance 1.0, number of receiver elements: 1100, spectral range of Y channel: 200-390 nm, of B channel: 390-1100 nm.
Operating cost price per hour starts at RUR 100.

SF-56 spectrophotometer (2012)
Measurement of transmission and optical density coefficients, scanning of the transmittance/absorbance spectrum in the specified wavelength interval. Spectral range of measurements: 190-1100. Transmittance measurement error is within ±0.5% in the 400-750 nm range, and within ±1% in the rest of the range.
Operating cost price per hour starts at RUR 100.

Multiphor II versatile horizontal electrophoresis and isoelectric focusing system (2008)
Applications include separation of complex protein mixtures, identification of protein fractions, evaluation of the purity of tissue protein fractions. Indispensable in the process of biological macromolecule isolation and purification. The system includes Multiphor horizontal electrophoresis unit; EPS 3501 XL power supply; MultiTemp III thermostatic circulator for pre-cooling; Hoefer Slab Gel Dryer 2000; Hoefer Processor Plus automated gel stainer; Image Quant 300 gel imaging system; VP 200 vacuum pump. Designed for separation and identification of proteins and their fragments.
Operating cost price per hour starts at RUR 200.

VersaFluor fluorometer (2006)
The device is designed for fluorescent detection in the 350-900 nm range. A special feature of the fluorometer is the possibility to select filters for detecting different fluorescent dyes. The detector is intended for quantifying PCR products, RNA, oligonucleotides, and proteins. Plastic or quartz cuvettes (1-3.5 ml) or microcuvettes (150-300 µl) are used.
Operating cost price per hour starts at RUR 200.

IR Prestige-21 Fourier-transform infrared spectrophotometer (2006)
Qualitative and quantitative analysis of liquid, solid and gaseous samples of varying nature. Outstandingly low detection limits are enabled by the use of a bright light source made of high-tech ceramic material, interferometer with high-reflectance Gold mirrors, and temperature-stabilized DLATGS detector. Operating range: 12500-240 cm-1. Resolution: 0.5ñì-1. Signal-to-noise ratio: 40000:1.
Operating cost price per hour starts at RUR 400.

FSM 1201 Fourier-transform infrared spectrometer (2006)
Detection and analysis of optical spectra in the infrared region. Qualitative and quantitative analysis for ecological control. Operating range 400-5000 cm-1. Resolution 1.0 cm-1. Absolute wave-number scale calibration error within ±0.1 cm-1. Standard deviation of 100% transmittance line (1950-2050 cm-1, resolution 4 cm-1, 20 scans) within 0.025%.
Operating cost price per hour starts at RUR 400.

Stayer high-performance isocratic liquid chromatograph (2007)
This isocratic chromatograph can be used on a daily basis for major HPLC routine analysis tasks. Being equipped with high-precision, high-pressure pumps with a wide range of flow rates (from 0.005 to 10 ml/min for the analytical and from 0.04 to 40 ml/min for the preparative head), detector cuvettes of varying volumes, and Rheodyne (7725i/9725) injectors, the instrument can be used to handle standard analytical-scale tasks as well as micro-scale and semi-preparative HPLC tasks. The material of the liquid pathway (ÐÅÅÊ) permits using the systems with any types of solvents, buffer solutions, and research objects (including those of protein nature). Features high sensitivity, precision and reproducibility of measurement results, automated processing of the results with reports produced in required form. Stayer chromatograph is included in the State register of measuring instruments.
Operating cost price per hour starts at RUR 500.

Stayer high-performance ionic liquid chromatograph (2007)
Designed for qualitative and quantitative analysis of inorganic and organic ion content in plant tissues. Detector characteristics: wavelength range: 190-600 nm, wavelength setting precision: ±1 nm, ramp-up time within 45 min. High sensitivity, reproducibility and speed of analysis (15 - 20 min for basic anions). Can operate with any column types and in single- and dual-column modes. Microprocessor control of the operation of the system’s modules. Computerized collection, processing and storage of chromatographic data. High-precision (<0.1°Ñ) cell temperature control in combination with high-precision electronic components of the conductivity detector and the use of high-performance columns provide the desired precision and reproducibility in the analysis of group 1 and 2 mineral cations, including ammonium cation, at up to 200 ppb (µkg/l) levels with direct sample injection in the single-column mode.
Operating cost price per hour starts at RUR 500.

Stayer liquid chromatograph with 102 Ì refractive index detector (2004)
Designed for analyzing complex multicomponent mixtures by liquid chromatography.
Operating cost price per hour starts at RUR 500.

Agilent 1200 series HPLC and 6210 TOF MS (ESI/APPI Source) system (2007)
Designed for identification of trace amounts of various components by means of their ionization with subsequent separation and detection by a time-of-flight mass analyzer.
Operating cost price per hour starts at RUR 500.

Shimadzu high-performance ionic liquid chromatograph (2003)
Quantitative analysis of a wide spectrum of organic and inorganic substances. Measurement range – 0.1-5120 µS/cm. Null signal noise within 0.004 msS/cm. Drift: in time – within 25 nS/cm per h; in temperature – 25 nS/cm·per °Ñ; cell – 0.25 µl; max pressure – 2.9 MPa; Operating temperature range – 25-55 °C. Maximum standard deviation of output signal for peak area – 3 %; for retention time – 0.5 %.
Operating cost price per hour starts at RUR 500.

Agilent 7890A gas chromatograph with automatic sampler (2013)
The chromatograph is designed for precise separation and identification of various complex organic mixture of natural genesis, such as the composition of fatty acids, bile acids, resin acids; various lipids, including cholesterol, etc. State-of-the-art gas chromatograph with digital data processing.
Operating cost price per hour starts at RUR 500.

Crystall 5000.1 benchtop gas chromatograph (2006)
Designed for analyzing complex multicomponent mixtures by gas chromatography.
Operating cost price per hour starts at RUR 500.

Chromatech Crystall-5000.2 gas chromatograph (2014)
The hardware-software system is designed for determining the component composition of various complex organic mixture of natural genesis, such as the composition of fatty acids, bile acids, resin acids; various lipids, including cholesterol, total lipids, phospholipids, etc.
Operating cost price per hour starts at RUR 500.

ÀÊÒÀ PRIME PLUS low-pressure liquid chromatograph (2006)
Liquid chromatography system. Designed for laboratory-based protein purification by all available methods. Fast-working. The system is compact, easy to use, supplied with a real-time monitor, pump, and fraction collector. Elution rate (max 50 ml/min) and pressure (up to l MPa) can be regulated. Programs are available for specific protein purification methods: low-pressure liquid chromatography, ion-exchange chromatography, affinity chromatography; can be set up to a certain pH value and run measurements at specified wavelengths in the UV spectrum.
Operating cost price per hour starts at RUR 500.

Maestro high-performance liquid chromatograph (2018)
Maestro high-performance liquid chromatograph combines classical, time-proven technologies with cutting-edge solutions in the analytical instrumentation industry. The flexible modular system enables optimal selection of configurations for handling a wide range of analytical tasks in conformance with GLP, ASTM, GOST standards. Diode array detector not only detects with high sensitivity substances with absorbance in the UV or visible spectral ranges but also facilitates their identification based on absorbance spectra. Powerful yet intuitively understandable Clarity software (in Russian), special software for servicing and fine tuning, easy access to all serviced parts render the Maestro high-performance liquid chromatograph user-friendly.
Operating cost price per hour starts at RUR 500.

Millichrom-6 multicolumn liquid chromatograph (2013)
Designed for separation of complex mixtures by high-performance liquid chromatography, identification and quantification of components of the separated mixture. Features an auto-injector with a capacity of 30 samples, high-precision dosing in 1 to 25 µl range, two 2500 µl microliter-syringe pumps, compact electronics unit assembled from dependable foreign-made parts. Device control and chromatographic information processing system based on an up-to-date computer and user-friendly UniChrom software working in Windows environment.
Operating cost price per hour starts at RUR 500.

Shimadzu LC-10Avp ion chromatograph with ÑDD 10-Avp conductivity detector (2003)
Quantitative analysis of a wide spectrum of organic and inorganic substances. Measurement range – 0.1-5120 µS/cm. Null signal noise within 0.004 msS/cm. Drift: in time within 25 nS/cm h, in temperature 25 nS/cm·°Ñ; cell – 0.25 µl; max pressure – 2.9 MPa; Operating temperature range – 25-55 °Ñ. Maximum standard deviation of output signal for peak area – 3 %; for retention time – 0.5 %.
Operating cost price per hour starts at RUR 500.

BioLogic LP System low-pressure chromatography system (2011)
Simple cost-effective low-pressure system suitable for purification of proteins and nucleic acids; can work in combination with preparative electrophoresis. Compact design; can be installed in a coldroom; programmable peristaltic pump with a flow range of 0.05 to 40 ml/min; valves for manual or automated sample loading; simultaneous control of five buffers; gradient mixer; UV module for protein and NA detection at 254/280; flow rate (max) 20 ml/min, 2-channel peristaltic pump; operating pressure (max) 30 psi (0.2 MPa); UV detector – 254/280 nm filters, resistance to aggressive chromatography solvents.
Operating cost price per hour starts at RUR 500.

CAMAG high-performance thin layer chromatography system (2016)
Designed for high-performance chromatography of lipids and fatty acids in plant and animal tissue samples. Semi-automatic sample dispenser Linomat 5 sprays samples for qualitative and quantitative HPTLC in the form of narrow bands; volume can vary from several to hundreds of µl for quantitative TLC; control through PC with winCATS software and keyboard; ADC 2 – innovative automatic developing chamber used in latest generation HPTLC. Its design and functionality enable fully automatic eluation. With the scanning densitometer Camag TLC Scanner fully controlled by integrated software, the device can be set up to the necessary measurement settings to generate reliable data in a user-friendly format. The instrument can be used for quantitative analysis of the generated densitometric data.
Operating cost price per hour starts at RUR 600.

OPTIMA LE-80K ultracentrifuge (2004)
Used for separation and isolation of proteins, lipoproteins, DNA, RNA plasmids, subcellular organelles, and viruses. Centrifuging speed up to 100000 rpm, g force 802400 x g. Cooling to -20°C.
Operating cost price per hour starts at RUR 200.

Allegra 64R high-speed centrifuge (2015)
Maximum speed 30000 rpm, 64400g, maximum capacity 4×85 ml; cooling to -20°C. Rotor set: F0630, F1010, F1202, F2402H.
Operating cost price per hour starts at RUR 200.

Mini-PROTEAN® Tetra Vertical Electrophoresis Cell (2010)
Used in biochemical studies for separation of complex protein mixtures, identification of protein fractions, determination of the purity of tissue protein fractions; a requisite step in the process of separation, isolation and purification of biological macromolecules.
Operating cost price per hour starts at RUR 200.


The formula for calculating the per hour cost price of using KarRC RAS Core Facility equipment (F) is the following:
F = À + B + C + D + E, where
À – depreciation of the equipment used in the activities and services, RUR per hour;
 – costs of maintenance and servicing of the key and auxiliary equipment used in the activities and services, RUR per hour;
Ñ – electricity costs, RUR per hour;
D - consumables, RUR per hour;
E – equipment operator wages, RUR per hour.

For KarRC RAS staff, the per hour cost price of using KarRC RAS CF equipment includes only the costs of consumables.


To apply for using KarRC RAS CF equipment contact Irina Sukhovskaya at sukhovskaya@inbox.ru

perechen_oborudovanija_ckp_karnc_ran_2021.pdf (1.03 Mb, total downloads: 321)


Core facility
Last modified: November 25, 2022